Reduced SIRT1 expression correlates with enhanced oxidative stress in compensated and decompensated heart failure

Sirtuin-1 (SIRT1) is a longevity factor in mammals initiating the cell survival mechanisms, and preventing ischemic injury in heart. In the etiopathogenesis of heart failure (HF), impairment in cardiomyocyte survival is a notable factor. Oxidative stress comprises a critical impact on cardiomyocyte...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Redox Biol
Prif Awduron: Akkafa, Feridun, Halil Altiparmak, Ibrahim, Erkus, Musluhittin Emre, Aksoy, Nurten, Kaya, Caner, Ozer, Ahmet, Sezen, Hatice, Oztuzcu, Serdar, Koyuncu, Ismail, Umurhan, Berrin
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Elsevier 2015
Pynciau:
Research Paper
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC4534572/
https://ncbi.nlm.nih.gov/pubmed/26233702
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.redox.2015.07.011
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