Efficacy of Adjuvant Trastuzumab for Patients With Human Epidermal Growth Factor Receptor 2–Positive Early Breast Cancer and Tumors ≤ 2 cm: A Meta-Analysis of the Randomized Trastuzumab Trials

PURPOSE: We compared efficacy of trastuzumab versus no trastuzumab in patients with small (≤ 2 cm) human epidermal growth factor receptor 2 (HER2) –positive breast cancer treated in randomized trials. METHODS: A meta-analysis was conducted using data from five of the six adjuvant trastuzumab trials....

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Veröffentlicht in:J Clin Oncol
Hauptverfasser: O'Sullivan, Ciara C., Bradbury, Ian, Campbell, Christine, Spielmann, Marc, Perez, Edith A., Joensuu, Heikki, Costantino, Joseph P., Delaloge, Suzette, Rastogi, Priya, Zardavas, Dimitrios, Ballman, Karla V., Holmes, Eileen, de Azambuja, Evandro, Piccart-Gebhart, Martine, Zujewski, Jo Anne, Gelber, Richard D.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society of Clinical Oncology 2015
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4534523/
https://ncbi.nlm.nih.gov/pubmed/26101239
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1200/JCO.2015.60.8620
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