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The Beta Cell in Its Cluster: Stochastic Graphs of Beta Cell Connectivity in the Islets of Langerhans

Pancreatic islets of Langerhans consist of endocrine cells, primarily α, β and δ cells, which secrete glucagon, insulin, and somatostatin, respectively, to regulate plasma glucose. β cells form irregular locally connected clusters within islets that act in concert to secrete insulin upon glucose sti...

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Publicat a:PLoS Comput Biol
Autors principals: Striegel, Deborah A., Hara, Manami, Periwal, Vipul
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2015
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4534467/
https://ncbi.nlm.nih.gov/pubmed/26266953
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1004423
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