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Ethanol Upregulates NMDA Receptor Subunit Gene Expression in Human Embryonic Stem Cell-Derived Cortical Neurons

Chronic alcohol consumption may result in sustained gene expression alterations in the brain, leading to alcohol abuse or dependence. Because of ethical concerns of using live human brain cells in research, this hypothesis cannot be tested directly in live human brains. In the present study, we used...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Xiang, Yangfei, Kim, Kun-Yong, Gelernter, Joel, Park, In-Hyun, Zhang, Huiping
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4534442/
https://ncbi.nlm.nih.gov/pubmed/26266540
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0134907
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