Keap1 regulates inflammatory signaling in Mycobacterium avium-infected human macrophages

Several mechanisms are involved in controlling intracellular survival of pathogenic mycobacteria in host macrophages, but how these mechanisms are regulated remains poorly understood. We report a role for Kelch-like ECH-associated protein 1 (Keap1), an oxidative stress sensor, in regulating inflamma...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Proc Natl Acad Sci U S A
Prif Awduron: Awuh, Jane Atesoh, Haug, Markus, Mildenberger, Jennifer, Marstad, Anne, Do, Chau Phuc Ngoc, Louet, Claire, Stenvik, Jørgen, Steigedal, Magnus, Damås, Jan Kristian, Halaas, Øyvind, Flo, Trude Helen
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: National Academy of Sciences 2015
Pynciau:
PNAS Plus
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC4534286/
https://ncbi.nlm.nih.gov/pubmed/26195781
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1423449112
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