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Plasmid replication initiator interactions with origin 13-mers and polymerase subunits contribute to strand-specific replisome assembly

Although the molecular basis for replisome activity has been extensively investigated, it is not clear what the exact mechanism for de novo assembly of the replication complex at the replication origin is, or how the directionality of replication is determined. Here, using the plasmid RK2 replicon,...

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Pubblicato in:Proc Natl Acad Sci U S A
Autori principali: Wawrzycka, Aleksandra, Gross, Marta, Wasaznik, Anna, Konieczny, Igor
Natura: Artigo
Lingua:Inglês
Pubblicazione: National Academy of Sciences 2015
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4534257/
https://ncbi.nlm.nih.gov/pubmed/26195759
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1504926112
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