Protein tyrosine phosphatase SAP-1 protects against colitis through regulation of CEACAM20 in the intestinal epithelium

Intestinal epithelial cells contribute to regulation of intestinal immunity in mammals, but the detailed molecular mechanisms of such regulation have remained largely unknown. Stomach-cancer–associated protein tyrosine phosphatase 1 (SAP-1, also known as PTPRH) is a receptor-type protein tyrosine ph...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Murata, Yoji, Kotani, Takenori, Supriatna, Yana, Kitamura, Yasuaki, Imada, Shinya, Kawahara, Kohichi, Nishio, Miki, Daniwijaya, Edwin Widyanto, Sadakata, Hisanobu, Kusakari, Shinya, Mori, Munemasa, Kanazawa, Yoshitake, Saito, Yasuyuki, Okawa, Katsuya, Takeda-Morishita, Mariko, Okazawa, Hideki, Ohnishi, Hiroshi, Azuma, Takeshi, Suzuki, Akira, Matozaki, Takashi
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2015
Assuntos:
PNAS Plus
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4534239/
https://ncbi.nlm.nih.gov/pubmed/26195794
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1510167112
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