The Gal(alpha 1-4)Gal-specific tip adhesin of Escherichia coli P-fimbriae is needed for pyelonephritis to occur in the normal urinary tract.

Nonobstructive acute pyelonephritis in humans is most often caused by P-fimbriated Escherichia coli. P-fimbriae are heteropolymeric fibers carrying a Gal(alpha 1-4)Gal-specific PapG adhesin at its distal end. The pyelonephritic strain DS17 expresses P-fimbriae from a single gene cluster. A mutant st...

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Main Authors: Roberts, J A, Marklund, B I, Ilver, D, Haslam, D, Kaack, M B, Baskin, G, Louis, M, Möllby, R, Winberg, J, Normark, S
格式: Artigo
語言:Inglês
出版: 1994
主題:
Research Article
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC45341/
https://ncbi.nlm.nih.gov/pubmed/7991552
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