The Gal(alpha 1-4)Gal-specific tip adhesin of Escherichia coli P-fimbriae is needed for pyelonephritis to occur in the normal urinary tract.

Nonobstructive acute pyelonephritis in humans is most often caused by P-fimbriated Escherichia coli. P-fimbriae are heteropolymeric fibers carrying a Gal(alpha 1-4)Gal-specific PapG adhesin at its distal end. The pyelonephritic strain DS17 expresses P-fimbriae from a single gene cluster. A mutant st...

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Detalhes bibliográficos

Publicado no:	Proc Natl Acad Sci U S A
Principais autores:	Roberts, J A, Marklund, B I, Ilver, D, Haslam, D, Kaack, M B, Baskin, G, Louis, M, Möllby, R, Winberg, J, Normark, S
Formato:	Artigo
Idioma:	Inglês
Publicado em:	National Academy of Sciences 1994
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC45341/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7991552/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.91.25.11889
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