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Approaching rational epitope vaccine design for hepatitis C virus with meta-server and multivalent scaffolding
Development of a prophylactic vaccine against hepatitis C virus (HCV) has been hampered by the extraordinary viral diversity and the poor host immune response. Scaffolding, by grafting an epitope onto a heterologous protein scaffold, offers a possible solution to epitope vaccine design. In this stud...
Guardat en:
| Publicat a: | Sci Rep |
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| Autors principals: | , , , , , , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Nature Publishing Group
2015
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4533164/ https://ncbi.nlm.nih.gov/pubmed/26238798 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep12501 |
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