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Augmented anti-angiogenesis activity of polysulfated heparin-endostatin and polyethylene glycol-endostatin in alkali burn-induced corneal ulcers in rabbits

Endostatin (ES) is an endogenous angiogenesis inhibitor that has the ability to inhibit tumor growth and metastasis. However, its clinical application is limited by a number of disadvantages, such as poor stability, short half-life and the requirement of high doses to maintain its efficacy. The chem...

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Publicat a:Exp Ther Med
Autors principals: LI, ZHAO-NA, YUAN, ZHONG-FANG, MU, GUO-YING, HU, MING, CAO, LI-JUN, ZHANG, YA-LI, GE, MING-XU
Format: Artigo
Idioma:Inglês
Publicat: D.A. Spandidos 2015
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4533158/
https://ncbi.nlm.nih.gov/pubmed/26622410
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/etm.2015.2602
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