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Succinylacetone as Primary Marker to Detect Tyrosinemia Type I in Newborns and its Measurement by Newborn Screening Programs

Tyrosinemia type I (TYR I) is caused by autosomal recessive fumarylacetoacetate hydrolase deficiency and is characterized by development of severe liver disease in infancy and neurologic crises. If left untreated, most patients die of liver failure in the first years of life. Intervention with medic...

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Salvato in:
Dettagli Bibliografici
Pubblicato in:Mol Genet Metab
Autori principali: De Jesús, Víctor R., Adam, Barbara W., Mandel, Daniel, Cuthbert, Carla D., Matern, Dietrich
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2014
Soggetti:
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4533100/
https://ncbi.nlm.nih.gov/pubmed/25066104
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ymgme.2014.07.010
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