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Enhancer of zeste homolog 2 silencing inhibits tumor growth and lung metastasis in osteosarcoma
The enhancer of zeste homolog 2 (EZH2) methyltransferase is the catalytic subunit of polycomb repressive complex 2 (PRC2), which acts as a transcription repressor via the trimethylation of lysine 27 of histone 3 (H3K27me3). EZH2 has been recognised as an oncogene in several types of tumors; however,...
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| Publicado no: | Sci Rep |
|---|---|
| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4533017/ https://ncbi.nlm.nih.gov/pubmed/26265454 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep12999 |
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