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Arsenic Trioxide Activate Transcription of Heme Oxygenase-1 by Promoting Nuclear Translocation of NFE2L2

In a previous study, we found that induced expression of Heme Oxygenase-1 (HO-1) is responsible for the resistance of human osteosarcoma MG63 cells to the chemotherapeutic agent arsenic trioxide (ATO). The present study was aimed at investigating the molecular mechanisms underlying the induction of...

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Publicat a:Int J Med Sci
Autors principals: Yue, Zhen, Zhong, Lingzhi, Mou, Yan, Wang, Xiaotong, Zhang, Haiying, Wang, Yang, Xia, Jianxin, Li, Ronggui, Wang, Zonggui
Format: Artigo
Idioma:Inglês
Publicat: Ivyspring International Publisher 2015
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4532976/
https://ncbi.nlm.nih.gov/pubmed/26283888
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7150/ijms.12450
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