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Enhancer additivity and non-additivity are determined by enhancer strength in the Drosophila embryo

Metazoan genes are embedded in a rich milieu of regulatory information that often includes multiple enhancers possessing overlapping activities. In this study, we employ quantitative live imaging methods to assess the function of pairs of primary and shadow enhancers in the regulation of key pattern...

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Detalhes bibliográficos
Publicado no:eLife
Main Authors: Bothma, Jacques P, Garcia, Hernan G, Ng, Samuel, Perry, Michael W, Gregor, Thomas, Levine, Michael
Formato: Artigo
Idioma:Inglês
Publicado em: eLife Sciences Publications, Ltd 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4532966/
https://ncbi.nlm.nih.gov/pubmed/26267217
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.07956
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