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Alpha-Lipoic Acid Attenuates Cerebral Ischemia and Reperfusion Injury via Insulin Receptor and PI3K/Akt-Dependent Inhibition of NADPH Oxidase

Alpha-lipoic acid (ALA) has various pharmacological effects such as antioxidative, anti-inflammatory, and antiapoptotic properties. In the present study, administration of ALA (40 mg/kg, i.p.) for 3 days resulted in a significant decrease in neuronal deficit score and infarct volume and a significan...

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Detalhes bibliográficos
Publicado no:Int J Endocrinol
Main Authors: Dong, Yinhua, Wang, Hongxin, Chen, Zefeng
Formato: Artigo
Idioma:Inglês
Publicado em: Hindawi Publishing Corporation 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4532939/
https://ncbi.nlm.nih.gov/pubmed/26294909
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2015/903186
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