The LIM-only transcription factor LMO2 determines tumorigenic and angiogenic traits in glioma stem cells

Glioblastomas (GBMs) maintain their cellular heterogeneity with glioma stem cells (GSCs) producing a variety of tumor cell types. Here we interrogated the oncogenic roles of Lim domain only 2 (LMO2) in GBM and GSCs in mice and human. High expression of LMO2 was found in human patient-derived GSCs co...

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Detalhes bibliográficos
Publicado no:Cell Death Differ
Main Authors: Kim, S-H, Kim, E-J, Hitomi, M, Oh, S-Y, Jin, X, Jeon, H-M, Beck, S, Kim, J-K, Park, C G, Chang, S-Y, Yin, J, Kim, T, Jeon, Y-j, Song, J, Lim, Y C, Lathia, J D, Nakano, I, Kim, H
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2015
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Original Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4532780/
https://ncbi.nlm.nih.gov/pubmed/25721045
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cdd.2015.7
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