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Non-Alcoholic Steatohepatitis: Limited Available Treatment Options but Promising Drugs in Development and Recent Progress Towards a Regulatory Approval Pathway

The prevalence of non-alcoholic fatty liver disease (NAFLD) and non-alcoholic steatohepatitis (NASH) is increasing world-wide in parallel to the increase of the obesity epidemic. Insulin resistance (IR) and the accumulation of triglyceride-derived toxic lipid metabolites play a key role in its patho...

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Detalhes bibliográficos
Publicado no:Drugs
Main Authors: Filozof, Claudia, Goldstein, Barry J., Williams, Richard N., Sanyal, Arun
Formato: Artigo
Idioma:Inglês
Publicado em: Springer International Publishing 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4532706/
https://ncbi.nlm.nih.gov/pubmed/26201461
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s40265-015-0437-3
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