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Synthesis and Evaluation of (99m)Tc-Labeled Folate-Tripeptide Conjugate as a Folate Receptor-Targeted Imaging Agent in a Tumor-Bearing Mouse Model

PURPOSE: The folate receptor (FR) is an attractive molecular target since it is overexpressed in a variety of human tumors. The purpose of the present study was to synthesize and evaluate the feasibility of a novel (99m)Tc-ECG-EDA (Glu-Cys-Gly-ethylenediamine)-folate as an FR-positive tumor imaging...

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Detalhes bibliográficos
Publicado no:Nucl Med Mol Imaging
Main Authors: Kim, Myoung Hyoun, Kim, Woo Hyoung, Kim, Chang Guhn, Kim, Dae-Weung
Formato: Artigo
Idioma:Inglês
Publicado em: Springer Berlin Heidelberg 2015
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4532691/
https://ncbi.nlm.nih.gov/pubmed/26279693
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s13139-015-0336-2
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