Long noncoding RNA-directed epigenetic regulation of gene expression is associated with anxiety-like behavior in mice

BACKGROUND: RNA-directed regulation of epigenetic processes has recently emerged as an important feature of mammalian differentiation and development. Perturbation of this regulatory system in the brain may contribute to the development of neuropsychiatric disorders. METHODS: RNA sequencing (RNA-seq...

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Publicado no:Biol Psychiatry
Main Authors: Spadaro, Paola A., Flavell, Charlotte R., Widagdo, Jocelyn, Ratnu, Vikram S., Troup, Michael, Ragan, Chikako, Mattick, John S., Bredy, Timothy W.
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4532653/
https://ncbi.nlm.nih.gov/pubmed/25792222
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.biopsych.2015.02.004
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