Deficiency of Lipoprotein Lipase in Neurons Decreases AMPA Receptor Phosphorylation and Leads to Neurobehavioral Abnormalities in Mice

Alterations in lipid metabolism have been found in several neurodegenerative disorders, including Alzheimer’s disease. Lipoprotein lipase (LPL) hydrolyzes triacylglycerides in lipoproteins and regulates lipid metabolism in multiple organs and tissues, including the central nervous system (CNS). Thou...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Yu, Tian, Taussig, Matthew D., DiPatrizio, Nicholas V., Astarita, Giuseppe, Piomelli, Daniele, Bergman, Bryan C., Dell’Acqua, Mark L., Eckel, Robert H., Wang, Hong
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2015
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4532501/
https://ncbi.nlm.nih.gov/pubmed/26263173
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0135113
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