Deficiency of Lipoprotein Lipase in Neurons Decreases AMPA Receptor Phosphorylation and Leads to Neurobehavioral Abnormalities in Mice

Alterations in lipid metabolism have been found in several neurodegenerative disorders, including Alzheimer’s disease. Lipoprotein lipase (LPL) hydrolyzes triacylglycerides in lipoproteins and regulates lipid metabolism in multiple organs and tissues, including the central nervous system (CNS). Thou...

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Udgivet i:PLoS One
Main Authors: Yu, Tian, Taussig, Matthew D., DiPatrizio, Nicholas V., Astarita, Giuseppe, Piomelli, Daniele, Bergman, Bryan C., Dell’Acqua, Mark L., Eckel, Robert H., Wang, Hong
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2015
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4532501/
https://ncbi.nlm.nih.gov/pubmed/26263173
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0135113
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