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Novel Epigenetic CREB-miR-630 Signaling Axis Regulates Radiosensitivity in Colorectal Cancer

BACKGROUND: miR-630 has been reported to be a modulator of several cancers, but the mechanism by which is it influences radioresistance remains unknown. We aimed to identify the molecular function of miR-630 and its regulatory mechanism in colorectal cancer (CRC) cell lines. METHODOLOGY: Overexpress...

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Détails bibliographiques
Publié dans:PLoS One
Auteurs principaux: Zhang, Yan, Yu, Jiang, Liu, Hao, Ma, Wenhui, Yan, Li, Wang, Jiefu, Li, Guoxin
Format: Artigo
Langue:Inglês
Publié: Public Library of Science 2015
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4532457/
https://ncbi.nlm.nih.gov/pubmed/26263387
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0133870
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