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Palmitoylethanolamide reduces pain-related behaviors and restores glutamatergic synapses homeostasis in the medial prefrontal cortex of neuropathic mice

BACKGROUND: Enhanced supraspinal glutamate levels following nerve injury are associated with pathophysiological mechanisms responsible for neuropathic pain. Chronic pain can interfere with specific brain areas involved in glutamate-dependent neuropsychological processes, such as cognition, memory, a...

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Bibliografische gegevens
Gepubliceerd in:Mol Brain
Hoofdauteurs: Guida, F., Luongo, L., Marmo, F., Romano, R., Iannotta, M., Napolitano, F., Belardo, C., Marabese, I, D’Aniello, A., De Gregorio, D., Rossi, F., Piscitelli, F., Lattanzi, R., de Bartolomeis, A., Usiello, A., Di Marzo, V., de Novellis, V., Maione, S
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: BioMed Central 2015
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4532244/
https://ncbi.nlm.nih.gov/pubmed/26260027
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13041-015-0139-5
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