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Deconvoluting heme biosynthesis to target blood-stage malaria parasites
Heme metabolism is central to blood-stage infection by the malaria parasite Plasmodium falciparum. Parasites retain a heme biosynthesis pathway but do not require its activity during infection of heme-rich erythrocytes, where they can scavenge host heme to meet metabolic needs. Nevertheless, heme bi...
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| Udgivet i: | eLife |
|---|---|
| Main Authors: | , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
eLife Sciences Publications, Ltd
2015
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4532139/ https://ncbi.nlm.nih.gov/pubmed/26173178 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.09143 |
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