The relationship between cisplatin-induced apoptosis and p53, bcl-2 and bax expression in human lung cancer cells

OBJECTIVES: Given the roles of bcl-2, bax and p53 in apoptosis, we investigated the effect of their expression on the response to cisplatin in order to understand the molecular events of cisplatin-resistance in lung cancers. METHODS: Three parental human lung cancer cell lines (PC9, PC14 and H69) an...

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Detalhes bibliográficos
Publicado no:Korean J Intern Med
Main Authors: Han, Ji-Youn, Chung, Yeun-Jun, Park, Sung Won, Kim, Jung Soo, Rhyu, Mun-Gan, Kim, Hoon-Kyo, Lee, Kyung Shick
Formato: Artigo
Idioma:Inglês
Publicado em: Korean Association of Internal Medicine 1999
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4531897/
https://ncbi.nlm.nih.gov/pubmed/10063313
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3904/kjim.1999.14.1.42
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