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The relationship between cisplatin-induced apoptosis and p53, bcl-2 and bax expression in human lung cancer cells
OBJECTIVES: Given the roles of bcl-2, bax and p53 in apoptosis, we investigated the effect of their expression on the response to cisplatin in order to understand the molecular events of cisplatin-resistance in lung cancers. METHODS: Three parental human lung cancer cell lines (PC9, PC14 and H69) an...
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| Publié dans: | Korean J Intern Med |
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| Auteurs principaux: | , , , , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
Korean Association of Internal Medicine
1999
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4531897/ https://ncbi.nlm.nih.gov/pubmed/10063313 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3904/kjim.1999.14.1.42 |
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