Emetine allows identification of origins of mammalian DNA replication by imbalanced DNA synthesis, not through conservative nucleosome segregation.

In the presence of emetine, an inhibitor of protein synthesis, nascent DNA on forward arms of replication forks in hamster cell lines containing either single or amplified copies of the DHFR gene region was enriched 5- to 7-fold over nascent DNA on retrograde arms. This forward arm bias was observed...

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Detaylı Bibliyografya
Asıl Yazarlar: Burhans, W C, Vassilev, L T, Wu, J, Sogo, J M, Nallaseth, F S, DePamphilis, M L
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 1991
Konular:
Research Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC453188/
https://ncbi.nlm.nih.gov/pubmed/1721870
Etiketler: Etiketle
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