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Novel inhibitor discovery against aromatase through virtual screening and molecular dynamic simulation: a computational approach in drug design
Inhibition of aromatase (CYTP450) as a key enzyme in the estrogen biosynthesis could result in regression of estrogen-dependent tumors and even preventing the promotion of breast cancer. Although today potent steroid and non-steroid inhibitors of aromatase are available, isoflavanone derivatives as...
Tallennettuna:
| Julkaisussa: | EXCLI J |
|---|---|
| Päätekijät: | , , , , |
| Aineistotyyppi: | Artigo |
| Kieli: | Inglês |
| Julkaistu: |
Leibniz Research Centre for Working Environment and Human Factors
2013
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| Aiheet: | |
| Linkit: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4531781/ https://ncbi.nlm.nih.gov/pubmed/26417225 |
| Tagit: |
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