Depletion of U3 small nucleolar RNA inhibits cleavage in the 5' external transcribed spacer of yeast pre-ribosomal RNA and impairs formation of 18S ribosomal RNA.

Multiple processing events are required to convert a single eukaryotic pre-ribosomal RNA (pre-rRNA) into mature 18S (small subunit), 5.8S and 25-28S (large subunit) rRNAs. We have asked whether U3 small nucleolar RNA is required for pre-rRNA processing in vivo by depleting Saccharomyces cerevisiae o...

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Detalhes bibliográficos
Publicado no:EMBO J
Main Authors: Hughes, J M, Ares, M
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 1991
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC453175/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1756730/
https://ncbi.nlm.nih.govhttps://doi.org/10.1002/j.1460-2075.1991.tb05001.x
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