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Molecular basis of Mycoplasma surface antigenic variation: a novel set of divergent genes undergo spontaneous mutation of periodic coding regions and 5' regulatory sequences.

Antigenic diversity is generated in the wall-less pathogen Mycoplasma hyorhinis by combinatorial expression and phase variation of multiple, size-variant membrane surface lipoproteins (Vlps). The unusual structural basis for Vlp variation was revealed in a cluster of related but divergent vlp genes,...

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Détails bibliographiques
Publié dans:EMBO J
Auteurs principaux: Yogev, D, Rosengarten, R, Watson-McKown, R, Wise, K S
Format: Artigo
Langue:Inglês
Publié: Nature Publishing Group 1991
Sujets:
Accès en ligne:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC453155/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1721868/
https://ncbi.nlm.nih.govhttps://doi.org/10.1002/j.1460-2075.1991.tb04983.x
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