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Parallel use of shake flask and microtiter plate online measuring devices (RAMOS and BioLector) reduces the number of experiments in laboratory-scale stirred tank bioreactors

BACKGROUND: Conventional experiments in small scale are often performed in a ‘Black Box’ fashion, analyzing only the product concentration in the final sample. Online monitoring of relevant process characteristics and parameters such as substrate limitation, product inhibition and oxygen supply is l...

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Detalhes bibliográficos
Publicado no:J Biol Eng
Main Authors: Wewetzer, S. J., Kunze, M., Ladner, T., Luchterhand, B., Roth, S., Rahmen, N., Kloß, R., Costa e Silva, A., Regestein, L., Büchs, J.
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2015
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4531433/
https://ncbi.nlm.nih.gov/pubmed/26265936
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13036-015-0005-0
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