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Evidence that Human Prostate Cancer is a ZIP1-Deficient Malignancy that could be Effectively Treated with a Zinc Ionophore (Clioquinol) Approach

Despite decades of research, no efficacious chemotherapy exists for the treatment of prostate cancer. Malignant prostate zinc levels are markedly decreased in all cases of prostate cancer compared to normal/benign prostate. ZIP1 zinc transporter down regulation decreases zinc to prevent its cytotoxi...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Chemotherapy (Los Angel)
Prif Awduron: Costello, Leslie C, Franklin, Renty B, Zou, Jing, Naslund, Michael J
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2015
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC4531383/
https://ncbi.nlm.nih.gov/pubmed/26273543
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4172/2167-7700.1000152
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