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Human GPR42 is a transcribed multisite variant that exhibits copy number polymorphism and is functional when heterologously expressed

FFAR3 (GPR41) is a G-protein coupled receptor for which short-chain fatty acids serve as endogenous ligands. The receptor is found on gut enteroendocrine L-cells, pancreatic β-cells, and sympathetic neurons, and is implicated in obesity, diabetes, allergic airway disease, and altered immune function...

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Publicat a:Sci Rep
Autors principals: Puhl III, Henry L., Won, Yu-Jin, Lu, Van B., Ikeda, Stephen R.
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group 2015
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4531286/
https://ncbi.nlm.nih.gov/pubmed/26260360
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep12880
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