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Haploinsufficiency of myostatin protects against aging-related declines in muscle function and enhances the longevity of mice

The molecular mechanisms behind aging-related declines in muscle function are not well understood, but the growth factor myostatin (MSTN) appears to play an important role in this process. Additionally, epidemiological studies have identified a positive correlation between skeletal muscle mass and l...

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Detalhes bibliográficos
Publicado no:Aging Cell
Main Authors: Mendias, Christopher L, Bakhurin, Konstantin I, Gumucio, Jonathan P, Shallal-Ayzin, Mark V, Davis, Carol S, Faulkner, John A
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley & Sons, Ltd 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4531085/
https://ncbi.nlm.nih.gov/pubmed/25808276
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/acel.12339
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