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Paternal age and telomere length in twins: the germ stem cell selection paradigm

Telomere length, a highly heritable trait, is longer in offspring of older fathers. This perplexing feature has been attributed to the longer telomeres in sperm of older men and it might be an ‘epigenetic’ mechanism through which paternal age plays a role in telomere length regulation in humans. Bas...

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Bibliographische Detailangaben
Veröffentlicht in:Aging Cell
Hauptverfasser: Hjelmborg, Jacob B, Dalgård, Christine, Mangino, Massimo, Spector, Tim D, Halekoh, Ulrich, Möller, Sören, Kimura, Masayuki, Horvath, Kent, Kark, Jeremy D, Christensen, Kaare, Kyvik, Kirsten O, Aviv, Abraham
Format: Artigo
Sprache:Inglês
Veröffentlicht: John Wiley & Sons, Ltd 2015
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4531084/
https://ncbi.nlm.nih.gov/pubmed/25865872
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/acel.12334
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