Age-related sensitivity to endotoxin-induced liver inflammation: Implication of inflammasome/IL-1β for steatohepatitis

Aging is associated with increased vulnerability to inflammatory challenge. However, the effects of altered inflammatory response on the metabolic status of tissues or organs are not well documented. In this study, we present evidence demonstrating that lipopolysaccharide (LPS)-induced upregulation...

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Bibliografiske detaljer
Udgivet i:Aging Cell
Main Authors: Chung, Ki Wung, Lee, Eun Kyeong, Kim, Dae Hyun, An, Hye Jin, Kim, Nam Deuk, Im, Dong Soon, Lee, Jaewon, Yu, Byung Pal, Chung, Hae Young
Format: Artigo
Sprog:Inglês
Udgivet: John Wiley & Sons, Ltd 2015
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Original Articles
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4531067/
https://ncbi.nlm.nih.gov/pubmed/25847140
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/acel.12305
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