Longevity and skeletal muscle mass: the role of IGF signalling, the sirtuins, dietary restriction and protein intake

Advancing age is associated with a progressive loss of skeletal muscle (SkM) mass and function. Given the worldwide aging demographics, this is a major contributor to morbidity, escalating socio-economic costs and ultimately mortality. Previously, it has been established that a decrease in regenerat...

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Bibliographic Details
Published in:Aging Cell
Main Authors: Sharples, Adam P, Hughes, David C, Deane, Colleen S, Saini, Amarjit, Selman, Colin, Stewart, Claire E
Format: Artigo
Language:Inglês
Published: John Wiley & Sons, Ltd 2015
Subjects:
Reviews
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4531066/
https://ncbi.nlm.nih.gov/pubmed/25866088
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/acel.12342
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