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Interferon-α and the calcifying microangiopathy in Aicardi–Goutières syndrome

Aicardi–Goutières syndrome is a leukoencephalopathy with calcifications and increased cerebrospinal fluid interferon-α. The relation between interferon-α and brain pathology is poorly understood. We report a patient with mutations in the disease-associated gene SAMHD1. Neuropathology showed an exten...

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Detalhes bibliográficos
Publicado no:Ann Clin Transl Neurol
Main Authors: Klok, Melanie D, Bakels, Hannah S, Postma, Nienke L, van Spaendonk, Rosalina M L, van der Knaap, Marjo S, Bugiani, Marianna
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley & Sons, Ltd 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4531060/
https://ncbi.nlm.nih.gov/pubmed/26273690
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/acn3.213
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