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Identification of a neurovascular signaling pathway regulating seizures in mice

OBJECTIVE: A growing body of evidence suggests that increased blood–brain barrier (BBB) permeability can contribute to the development of seizures. The protease tissue plasminogen activator (tPA) has been shown to promote BBB permeability and susceptibility to seizures. In this study, we examined th...

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Podrobná bibliografie
Vydáno v:Ann Clin Transl Neurol
Hlavní autoři: Fredriksson, Linda, Stevenson, Tamara K, Su, Enming J, Ragsdale, Margaret, Moore, Shannon, Craciun, Stefan, Schielke, Gerald P, Murphy, Geoffrey G, Lawrence, Daniel A
Médium: Artigo
Jazyk:Inglês
Vydáno: John Wiley & Sons, Ltd 2015
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4531055/
https://ncbi.nlm.nih.gov/pubmed/26273685
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/acn3.209
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