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Identification of a neurovascular signaling pathway regulating seizures in mice

OBJECTIVE: A growing body of evidence suggests that increased blood–brain barrier (BBB) permeability can contribute to the development of seizures. The protease tissue plasminogen activator (tPA) has been shown to promote BBB permeability and susceptibility to seizures. In this study, we examined th...

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Bibliographic Details
Published in:Ann Clin Transl Neurol
Main Authors: Fredriksson, Linda, Stevenson, Tamara K, Su, Enming J, Ragsdale, Margaret, Moore, Shannon, Craciun, Stefan, Schielke, Gerald P, Murphy, Geoffrey G, Lawrence, Daniel A
Format: Artigo
Language:Inglês
Published: John Wiley & Sons, Ltd 2015
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4531055/
https://ncbi.nlm.nih.gov/pubmed/26273685
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/acn3.209
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