Kidney Dysfunction in Adult Offspring Exposed In Utero to Type 1 Diabetes Is Associated with Alterations in Genome-Wide DNA Methylation

BACKGROUND: Fetal exposure to hyperglycemia impacts negatively kidney development and function. OBJECTIVE: Our objective was to determine whether fetal exposure to moderate hyperglycemia is associated with epigenetic alterations in DNA methylation in peripheral blood cells and whether those alterati...

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محفوظ في:
التفاصيل البيبلوغرافية
الحاوية / القاعدة:PLoS One
المؤلفون الرئيسيون: Gautier, Jean-François, Porcher, Raphaël, Abi Khalil, Charbel, Bellili-Munoz, Naima, Fetita, Lila Sabrina, Travert, Florence, Choukem, Simeon-Pierre, Riveline, Jean-Pierre, Hadjadj, Samy, Larger, Etienne, Boudou, Philippe, Blondeau, Bertrand, Roussel, Ronan, Ferré, Pascal, Ravussin, Eric, Rouzet, François, Marre, Michel
التنسيق: Artigo
اللغة:Inglês
منشور في: Public Library of Science 2015
الموضوعات:
Research Article
الوصول للمادة أونلاين:https://ncbi.nlm.nih.gov/pmc/articles/PMC4530883/
https://ncbi.nlm.nih.gov/pubmed/26258530
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0134654
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