Identification of molecular contacts between the U1 A small nuclear ribonucleoprotein and U1 RNA.

We recently determined the crystal structure of the RNP domain of the U1 small nuclear ribonucleoprotein A and identified Arg and Lys residues involved in U1 RNA binding. These residues are clustered around the two highly conserved segments, RNP1 and RNP2, located in the central two beta strands. We...

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Autores principales: Jessen, T H, Oubridge, C, Teo, C H, Pritchard, C, Nagai, K
Formato: Artigo
Lenguaje:Inglês
Publicado: 1991
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Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC453073/
https://ncbi.nlm.nih.gov/pubmed/1833186
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