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CYP3A5 genotyping for assessing the efficacy of treatment with simvastatin and atorvastatin
In this work, we examined the impact of polymorphism in the cytochrome P450 (CYP) 3A5 gene, CYP3A5*1 (6986A > G, rs 776746), on the reduction in the lipid levels caused by simvastatin and atorvastatin. We studied 350 hyperlipidemic patients who received 10-40 mg of atorvastatin (n = 175) or simva...
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| 出版年: | Genet Mol Biol |
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| 主要な著者: | , , , , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Sociedade Brasileira de Genética
2015
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4530653/ https://ncbi.nlm.nih.gov/pubmed/26273214 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1590/S1415-4757382220140239 |
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