Genotyping of CYP2C9 and VKORC1 in the Arabic Population of Al-Ahsa, Saudi Arabia

Polymorphisms in the genes encoding CYP2C9 enzyme and VKORC1 reductase significantly influence the dose variability of coumarinic oral anticoagulants (COAs). Substantial inter- and intraethnic variability exists in the frequencies of CYP2C9 (∗)2 and (∗)3 and VKORC1 –1639A alleles. However, the preva...

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Main Authors: Alzahrani, Abdullah M., Ragia, Georgia, Hanieh, Hamza, Manolopoulos, Vangelis G.
Format: Artigo
Jezik:Inglês
Izdano: Hindawi Publishing Corporation 2013
Teme:
Research Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3613048/
https://ncbi.nlm.nih.gov/pubmed/23586031
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2013/315980
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