Quantitative activation-induced manganese-enhanced MRI reveals severity of Parkinson’s disease in mice

We demonstrate that activation-induced manganese-enhanced magnetic resonance imaging with quantitative determination of the longitudinal relaxation time (qAIM-MRI) reveals the severity of Parkinson’s disease (PD) in mice. We first show that manganese ion-accumulation depends on neuronal activity. A...

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Bibliografische gegevens
Gepubliceerd in:Sci Rep
Hoofdauteurs: Kikuta, Satomi, Nakamura, Yukiyo, Yamamura, Yukio, Tamura, Atsushi, Homma, Noriyasu, Yanagawa, Yuchio, Tamura, Hajime, Kasahara, Jiro, Osanai, Makoto
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Nature Publishing Group 2015
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Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4530460/
https://ncbi.nlm.nih.gov/pubmed/26255701
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep12800
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