Human Islets Have Fewer Blood Vessels than Mouse Islets and the Density of Islet Vascular Structures Is Increased in Type 2 Diabetes

Human and rodent islets differ substantially in several features, including architecture, cell composition, gene expression and some aspects of insulin secretion. Mouse pancreatic islets are highly vascularized with interactions between islet endothelial and endocrine cells being important for islet...

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Publicat a:J Histochem Cytochem
Autors principals: Brissova, Marcela, Shostak, Alena, Fligner, Corinne L., Revetta, Frank L., Washington, Mary K., Powers, Alvin C., Hull, Rebecca L.
Format: Artigo
Idioma:Inglês
Publicat: SAGE Publications 2015
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Articles
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4530394/
https://ncbi.nlm.nih.gov/pubmed/26216139
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1369/0022155415573324
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