Aberrant melanogenesis and melanocytic tumour development in transgenic mice that carry a metallothionein/ret fusion gene.

We generated four independent transgenic mouse lines that showed severe melanosis of the whole body by introducing the ret oncogene fused to the mouse metallothionein (MT)-I promoter-enhancer (MT/ret). Whereas melanogenesis was accelerated without distinct proliferative disorders in one line, melano...

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Hlavní autoři: Iwamoto, T, Takahashi, M, Ito, M, Hamatani, K, Ohbayashi, M, Wajjwalku, W, Isobe, K, Nakashima, I
Médium: Artigo
Jazyk:Inglês
Vydáno: 1991
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Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC453039/
https://ncbi.nlm.nih.gov/pubmed/1915289
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