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Clinical potential of pacritinib in the treatment of myelofibrosis

Myelofibrosis (MF) is a myeloid disorder caused by a clonal hematopoietic stem-cell proliferation associated with activation of the Janus kinase (JAK) signal transducer and activator of transcription (STAT) signaling pathways. Patients with MF often develop severe splenomegaly, marked symptom burden...

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Foilsithe in:Ther Adv Hematol
Main Authors: Duenas-Perez, Ana B., Mead, Adam J.
Formáid: Artigo
Teanga:Inglês
Foilsithe: SAGE Publications 2015
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4530369/
https://ncbi.nlm.nih.gov/pubmed/26288713
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/2040620715586527
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