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Integrating between-host transmission and within-host immunity to analyze the impact of varicella vaccination on zoster

Varicella-zoster virus (VZV) causes chickenpox and reactivation of latent VZV causes herpes zoster (HZ). VZV reactivation is subject to the opposing mechanisms of declining and boosted VZV-specific cellular mediated immunity (CMI). A reduction in exogenous re-exposure ‘opportunities’ through univers...

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Bibliografske podrobnosti
izdano v:eLife
Main Authors: Ogunjimi, Benson, Willem, Lander, Beutels, Philippe, Hens, Niel
Format: Artigo
Jezik:Inglês
Izdano: eLife Sciences Publications, Ltd 2015
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4530225/
https://ncbi.nlm.nih.gov/pubmed/26259874
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.07116
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