The flow cytometry-defined light chain cytoplasmic immunoglobulin index and an associated 12-gene expression signature are independent prognostic factors in multiple myeloma

As part of Total Therapy (TT) 3b, baseline marrow aspirates were subjected to two-color flow cytometry of nuclear DNA content and cytoplasmic immunoglobulin (DNA/CIG) as well as plasma cell gene expression profiling (GEP). DNA/CIG-derived parameters, GEP and standard clinical variables were examined...

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Detalhes bibliográficos
Publicado no:Leukemia
Main Authors: Papanikolaou, X, Alapat, D, Rosenthal, A, Stein, C, Epstein, J, Owens, R, Yaccoby, S, Johnson, S, Bailey, C, Heuck, C, Tian, E, Joiner, A, van Rhee, F, Khan, R, Zangari, M, Jethava, Y, Waheed, S, Davies, F, Morgan, G, Barlogie, B
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2015
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4530205/
https://ncbi.nlm.nih.gov/pubmed/25753926
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/leu.2015.65
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