miR-509 suppresses brain metastasis of breast cancer cells by modulating RhoC and TNF α

The median survival time of breast cancer patients with brain metastasis is less than 6 months, and even a small metastatic lesion often causes severe neurological disabilities. Because of the location of metastatic lesions, a surgical approach is limited and most chemotherapeutic drugs are ineffect...

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Udgivet i:Oncogene
Main Authors: Xing, Fei, Sharma, Sambad, Liu, Yin, Mo, Yin-Yuan, Wu, Kerui, Zhang, Ying-Yu, Pochampally, Radhika, Martinez, Luis A, Lo, Hui-wen, Watabe, Kounosuke
Format: Artigo
Sprog:Inglês
Udgivet: 2015
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4530094/
https://ncbi.nlm.nih.gov/pubmed/25659578
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/onc.2014.412
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